Boots No 7 Protect and Perfect has created a stir worldwide after being aired on the British BBC Horizons in 2007. The question on many people’s lips - what is the secret ingredient in the product?

Boots number 7 contains Palmitoyl Pentapeptide -3

The full Protect and Perfect ingredient list is located further in the article, but the active ingredient that is speculated to reverse photo-aging is Palmitoyl Pentapeptide –3, also known as Matrixyl.

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Australian alternative to the Boots No 7.

Research on Palmitoyl Pentapeptide to date.

Studies of Palmitoyl pentapeptide-3 existed prior to the latest research by Professor Griffiths but these had been sponsored by the manufacturers (Sederma and Proctor & Gamble)

The studies compared Palmitoyl pentapeptide-3 to retinol and showed an average of 9 percent increase in skin thickness observed after 4 months for both Palmitoyl pentapeptide-3 and retinol. However the Palmitoyl pentapeptide increased skin thickness faster than the retinol and without the side effects of the later. Source here and here

Full ingredient list for Boots no 7 Protect and Perfect

Cyclopentasiloxane
Aqua
Butylene glycol
Dimethicone cross polymer
Cyclohexasiloxane
Glycerin
Dimethicone copolyol
Sodium ascorbyl phosphate
Polysorbate 20
Magnesium sulphate
Phenoxyethanol
Sodium PCA
Retinyl palmitate
Methylparaben
Propylene glycol
Lupinus albus
Carbomer
Butylparaben
Ethylparaben
Propylparaben
Isobutylparaben
Panax ginseng
Morus Alba
Tocopherol
Palmitoyl pentapeptide-3

Australian alternative 5% peptide serum

Because of the lack of availability of Boots No 7 I had a serum developed with the same active ingredients as the Boots No 7 - this peptide serum is available through our clinic. It is a lighter serum than the original more suited to Australia’s humid conditions. The percentage of Palmitoyl pentapeptide in the serum is 6% and it retails for $44 Australian (50ml). An advantage of this particular Palmitoyl pentapeptide serum is, that unlike the original it does not contain parabens as a preservative.

Contact us if you are interested in buying
an Australian alternative to the Boots No 7.

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Considering the lack of availability of the Boots no 7 product in Australia, what alternatives are available? First a little background on the Boots product.

Boot No 7 Protect and Perfect Serum- active ingredient.

Palmitoyl Pentapeptide is the active ingredient of Boots No 7. It is a synthetic peptide that was developed for use as a skin care ingredient to stimulate collagen production and thus provide a skin anti-wrinkle benefit.

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Australian alternative to Boots No 7

How does Palmitoyl Pentapeptide stimulate collagen production?

Palmitoyl Pentapeptide was developed to mimic natural peptides found in the skin called Matrikines. These small peptides are formed when skin proteins are damaged and broken down and work as cell messengers which regulate the skin repair and wound healing process - leading to increased production of collagen. Very clever!

Boots No 7 - the Manchester study.

The Manchester study proved that it had a similar effect to retinoic acid.

Testing was carried out on volunteers, not in test tubes, and by measuring levels of fibrillin, which is one of the skin’s proteins that are affected by sun damage to skin.

The study showed that the serum began to repair damage to the skin’s structure.

Women volunteers who tested the products found measurable improvements in wrinkle depth.

Previous studies on Palmitoyl Pentapeptide

Palmitoyl pentapeptide shown to be effective at 3-5% concentration.

Skin biopsies conducted indicated palmitoyl pentapeptide triggered growth in elastin and collagen.

Demonstrated improvements in skin roughness, wrinkle volume, and wrinkle depth.

Australian alternative 5% peptide serum

Because of the lack of availability of Boots No 7 I had a serum developed with the same active ingredients as the Boots No 7 - this peptide serum is available through our clinic. It is a lighter serum than the original more suited to Australia’s humid conditions. The percentage of Palmitoyl pentapeptide in the serum is 6% and it retails for $44 Australian (50ml). An advantage of this particular Palmitoyl pentapeptide serum is, that unlike the original it does not contain parabens as a preservative.

Contact us if you are interested in buying
an Australian alternative to the Boots No 7.

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Boots No 7 ‘Protect and Perfect’ or ‘Restore and Renew’

Marketed under Protect and Perfect in the UK and Restore and Renew in the USA, the product is currently not available in Australia. Judging by the company’s inability to keep up with large Northern hemisphere markets it will be a long time in coming. Since the BBC Horizons aired its show ‘Dr Reagan’s Beauty Parlour’ the product vanished from the shelves.

Boots No 7 Serum - What Is Different?

1. The active ingredient, palmitoyl pentapeptide, is the first product to meet the results achieved from prescription retinoids as an anti-wrinkle treatment.

2. The product has blown the cover: you do not need to pay exorbitant amounts of money to get good skin care product.

Palmitoyl Pentapeptide

The active ingredient in Boots No 7, Palmitoyl Pentapeptide is not new, it is manufactured by Sederma and clinical studies on its effectiveness existed prior to the latest research by Professor Griffiths at the Manchester University.

Professor Griffiths: “At both basic science and clinical levels Boots No7 Protect & Perfect has been shown scientifically to repair photo-aged skin and improve the fine wrinkles associated with photo-ageing.” Reported in Daily Mail 2nd April

Boots No 7 serum a revolution in skin care cost

The original BBC program compared it to the much-hyped La Prairie Cellular range which could cost as much as £229 for a small 30ml pot. The Boots No 7 costing £17 won hands down. The real revolution - proven fact: good skin care need not cost a fortune.

Australian alternative 5% peptide serum

Because of the lack of availability of Boots No 7 I had a serum developed with the same active ingredients as the Boots No 7 - this peptide serum is available through our clinic. It is a lighter serum than the original more suited to Australia’s humid conditions. The percentage of Palmitoyl pentapeptide in the serum is 6% and it retails for $44 Australian (50ml). An advantage of this particular Palmitoyl pentapeptide serum is, that unlike the original it does not contain parabens as a preservative.

Contact us if you are interested in buying
an Australian alternative to the Boots No 7.

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Boots No 7 Protect and Perfect is a silicone based serum that contains a good mix of antioxidants A (retinyl palmitate), C (Sodium ascorbyl phosphate), E (tocopherol) mulberry extract and ginseng.

However the active ingredient that ia believed to cause the decrease in wrinkle depth reported in the media is a palmitoyl-pentapeptide. It is not a new ingredient however prior studies where sponsored by Sederma the company that manufacturers it.

Australian alternative 5% peptide serum

Because of the lack of availability of Boots No 7 I had a serum developed with the same active ingredients as the Boots No 7 - this peptide serum is available through our clinic. It is a lighter serum than the original more suited to Australia’s humid conditions. The percentage of Palmitoyl pentapeptide in the serum is 6% and it retails for $44 Australian (50ml). An advantage of this particular Palmitoyl pentapeptide serum is, that unlike the original it does not contain parabens as a preservative.

Contact us if you are interested in buying
an Australian alternative to the Boots No 7.

A final word from the scientist who formulated this product

The man responsible for the Boots’ wrinkle-buster is Steve Barton, a biologist who spent 12 years in dermatological research before joining the chain as a scientific adviser 17 years ago has this to say about the Protect and Perfect Serum.

• “The lotion takes 4-8 weeks to work.”
• “Wrinkles won’t disappear. This is not a cosmetic injections, but they are significantly improved.”
• The serum has no magic ingredient. It is just a combination of products,”

Contact us if you are interested in buying
an Australian alternative to the Boots No 7.

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